A Major Step on the Road to Understanding a Unique Posttranslational Modification and Its Role in a Genetic Disease
نویسنده
چکیده
The posttranslational conversion of cysteine to C(alpha)-formylglycine in the catalytic site of mammalian sulfatases is deficient in the rare but devastating disorder multiple sulfatase deficiency (MSD). Two papers in this issue of Cell report the cloning of a gene responsible for this activity.
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عنوان ژورنال:
- Cell
دوره 113 شماره
صفحات -
تاریخ انتشار 2003